2004 Scholars
- Ezana Azene, Johns Hopkins University
- Gene Therapy for Peripheral Neuropathic Pain
- Melynda Barnes, Mount Sinai School of Medicine
- Immunohistochemical analysis of spinal cords from disulfiram-treated G86R superoxide dismutase-1 transgenic mice
- Ala Berdichevsky, Massachusetts Institute of Techonology
- Identification of molecular targets of sir-2.1 gene, which promotes extension of lifespan of the nematode Caenorhabditis elegans
- Eric Hau-Yun Chang, New York University
- Receptor dysfunction in double knock-in APP+PS1 mice
- Robi Goswami, Duke University
- Regulation of the Platelet-Derived Growth Factgor Receptor-B by G Protein-Coupled Receptor Kinase-2
- Jennifer Greenhall, University of California, San Diego
- The impact of fgf1 and fgf2 on the preservation of cortical neurons in the aging mouse
- Shilpa Iyer, University of Georgia
- Klstn-M1 a novel yeast model system to study telomere capping defects and recombinational telomere elongation
- William Ja, California Institute of Technology
- Characterization of methuselah, a drosophila G protein-coupled receptor associated with longevity
- Young Mok Jang, University of Florida, Gainesville
- Long-term caloric restriction (CR) as a strategy to prevent sarcoplasmic reticulum (SR) stress induced cardiomyocytes apoptosis in vivo
- Jennifer Kwong, Weill Medical College of Cornell University
- Modulation of mitochondrial homeostasis by Bcl-2 in cells with mitochondrial DNA mutations
- Janelle Lauer-Fields, Florida Atlantic University
- Engineering and expression of ADMTS-4 and ADMTS-5, proteolytic enzymes involved in osteoarthritis progression
- Maria Lehtinen, Harvard University
- Characterization of the role of MST1 in oxidative stress and aging in caenorhabditis elegans
- Jacqueline Maffucci, University of Texas at Austin
- Hypothalamic Mechanisms for Reproductive Senescence in Aging Female Rats: Roles of NMDA Receptors and GnRH Neurons
- Patrick McLaughlin, University of Washington
- Proteomic Analysis of Proteins related to Inflammation in Parkinson’s Disease
- Kathryn Moynihan, Washington University
- Deacetylation of the forkhead transcription factor FOX01 by mammalian Sir2a negarively regulates insulin gene expression in pancreatic b cells
- Xuan Nguyen, University of Kentucky
- Age-Dependent Alterations in Dopamine and the Nigrostriatal System in Prodynophin Knockout Mice
- Mohammed Ozair, Aga Khan University
- Analysis of Neural Stem Cell migration towards Brain Tumors by in vivo phage display Annalise Paaby, University of Pennsylvania: Selection and Gene regulation of senescence in natural populations of drosophila
- Carlos Pantoja, University of California, San Francisco
- The involvement of DAF-16 and HSF-1 in the regulation of small heat shock protein genes
- Julie Plowden, Emory University
- Effects of Aging on the Kinetics and Strength of T cell-Antigen Presenting Cell Interactions
- Adolfo Sanchez-Blanco, University of Connecituct Health Center
- UCP5 deficiency mimics caloric restriction in drosophila melanogaster
- Kim Sciarretta, University of Chicago
- Modeling and Intermediate of beta-amyloid fibril formation
- Kun-Chih Kelvin Tsai, Harvard University
- Heterotypic interactions between stress-induced prematurely senescent stroma and neighboring epithelial cells in aging and cancer
- Lisa Whitson, University of Texas Health Science Center at San Antonio
- Monomerization and Amyloid Formation of FALS-Associated Cu-Zn Superoxide Dismutase Mutants
- Brice Williams, Medical University of South Carolina
- Altered Neurotrophin Release in Age-Related Dementia
2003 Scholars
- Scott B. Berger, University of Michigan
- The Use of Glycosidases as a Means of Correcting Age-Dependent Deficiencies of T-cell Function
- Jennifer Capla, New York University
- Investigating the Role of Adult Vascular Stem Cells in the Pathogenesis of Age-Related Disease
- Marci L. Chew, University of Pittsburgh
- Serum Anticholinergicity at Specific Muscarinic Receptor Subtypes
- Daniel J. Durand, Johns Hopkins University
- Myocardial Regeneration by Bone-marrow Derived Stem Cells in Old Versus Young Wistar Rats
- Andrew A. Grimm, Washington University
- The Functional Relationship Between an NAD Biosynthesis Enzyme and the NAD-Dependent Deacetylase, SIR2, in Mammals
- Mary A. Hancock, University of Utah
- Comparison of the Levels of Oxidative Damage Among European Mitochondrial Haplogroups Using Phylogenetic Analysis
- Jaime M. Hatcher, Emory University
- Effects of Chronic Dieldrin Exposure to Organotypic Slice Cultures of Rat Stratum and Nigra
- Kerry L. Hildreth, Duke University
- Molecular Mechanisms for Regulation of the Platelet-derived Growth Factor Receptor Beta by Serine Phosphorylation
- Renee Ho, University of Southern Alabama
- Enhancing Mitochondrial DNA Repair of Oxidative Damage as a Strategy to Delay the Effect of Aging in Neurons
- Steven Hobbs, University of Colorado
- The Role of Estrogen in Cortisol Induced Beta-Amyloid Production and Toxicity
- Troy A. Hornberger, University of Illinois, Chicago
- Regulation of Protein Synthesis Through Stretch Induced Signaling Events in Aging Skeletal Muscle
- Matthew R. Hosler, University of Medicine and Dentistry of New Jersey
- The Role of Oxidation in the TGF-beta Cataract Model
- James G. Jackson, University of Texas Health Science Center at San Antonio
- Role of the Novel Transcription Factor MRG15 in Cell Proliferation and Senescence Escape
- Hanyu Maggie Liang, University of Texas Health Science Center at San Antonio
- Characterization of Transgenic Mice Overexpressing Thioredoxin2 (Trx2)
- Janelle Mallet, University of Connecticut
- Effect of Parathyroid Hormone on Osteoblast Proliferation and Apoptosis in Fgf2 Knockout Mice
- Julien Muffat, Caltech
- Characterization of the Drosophila Aolipoprotein D Homolog as a Novel Gene Influencing Lifespan and Stress Resistance
- Tung Hoang Ngo, Ph.D., Western University College of Medicine
- Effect of Dietary Fat on Androgen-independent Prostate Tumor Growth in Scid Mice
- Anirban Paul, Howard University
- Novel Regulators of Manganese Superoxide Dismutase Gene Transcription in Drosophila
- Richard J. Perrin, University of Illinois at Urbana-Champaign
- Analysis of Polyunsaturated Fatty Acid-induced Modification of Alpha-Synuclein, a Protein Involved in Neurodegenerative Disease
- Deepa Pikle, University of Maryland
- Premature Aging: A defective helicase-Topoisomerase Interaction in DNA Metabolism
- Amy Pooler, Massachusetts Institute of Technology
- Investigating Age-related Memory Impairment: The Role of Cholesterol in Synaptic Protein Expression and Membrane Formation in the Hippocampus
- Davis C. Ryman, Case Western Reserve University
- A Genome Scan for Quantitative Trait Loci Controlling Beta-Amyloid Production and Deposition in a Transgenic Mouse Model of Alzheimer’s Disease
- Megha Satyanarayana, University of Southwest Medical Center
- A Rapid Fluorescence-based Screen for Long Lived C. elegans Mutants
- Ganesh Shankar, Harvard Medical School
- Effects of apolipoprotein E and a1j-antichymotrypsin on in vivo production and stabilization of natural amyoid beta-protein oligomers
- Jason D. Shepherd, Johns Hopkins University
- The Involvement of the Immediate Early Gene ARC in Endoytosis of Presenilin1 and APP Processing: Implications for Alzheimer’s Disease
- Tiffany E. Shubert, University of North Carolina, Chapel Hill
- Effects of Exercise on Angiogenesis in the Hippocampus of Mice
- Brian Silvia, University of Connecticut
- Targeted Expression of Putative Drosophila Uncoupling Protein and its Effect on Longevity
- Wook Song, Texas A&M University
- Effect of Exercise Training on Age-induced Upregulation of the iNOS Signaling Pathway in Skeletal Muscle
- Liou Sun, Southern Illinois University
- The Effect of Dwarfism and Caloric Restriction on Synaptophysin Expression in the Mouse Hippocampus
- Susan E. Swanberg, J.D., University of California, Davis
- Avian Cells in vitro: A Model System for the Study of Telomere Length Regulation and Replicative Senescence
2002 Scholars
- Trinity Bivalacqua, Tulane University School of Medicine
- Role of Superoxide in the Pathophysiology of Age-Related Erectile Dysfunction Influence of In Vivo Gene Transfer of Superoxide Dismutase
- Jinsook Chang, UTHSCSA
- Profiling of Mitochondrial Proteins by 2D. Gel Electrophoresis in Wild Type and Heterozygous MnSOD Mice with Age
- Abbie Connoy, Wake Forest University
- Aging and the Regulation of the Interleukin-1-Receptor-Associated Kinase in Murine Splenocytes
- Danielle Day, University of Colorado Health Science Center
- Effects of Age-Related Decline in Sex Hormones on Resting Energy Expenditure
- Raina Gay, Tufts University
- The Effect of Vitamin E on Secondary Bacterial Infection Following Influenza Infection in Old Mice
- William Go, University of California, San Diego
- Elucidating the Function of NFAT5 Possible Cell Cycle Modulator in Response to Oxidative Stress, UV/Ionizing Radiation and Hypertonicity
- Mark Haussmann, Iowa State University
- How Do Long-Lived Organisms Delay Senescence? Development of Appropriate Models and Techniques
- Jason Hinman, Boston University School of Medicine
- The Characterization of Nodal Abnormalities in the Aging Brain
- Cheng Huang, Washington University School of Medicine
- Identification of Genes Involved in Caenorhabditis elegans Aging
- Cheryl Jansen, University of Minnesota
- Proteome Analysis of Retinal Proteins
- Kara Johnson, Loyola University Medical Center
- Effect of Age on B-Lymphopoiesis and the Maintenance of the Mature B Cell Compartment
- Nathan LeBraseur, Boston University
- Neuregulin/ErbB Signaling in Skeletal Muscle Aging & Atrophy
- Sandy Li, University of Michigan
- Expression Analysis of Type II IP3 Receptor in Aging Retina
- Lina Li, University of Alabama at Birmingham
- Age-Related Thymic Involution in IL-12B Knockout Mice
- Paul Lockman, Texas Tech. University Health Science Center
- Targeted Brain Delivery of Novel Nanoparticles via the Blood-brain Barrier Choline Transporter
- Carrie Lyons, Queen’s University
- The Impact of Mitochondrial Ultrastructure on Cellular Physiology
- Deanna Marchionini, Rush-Presbyterian-St. Luke’s Medical Center
- Melatonin Treatment for Optimal Graft Survival in an Aged Rat Model of Parkinson’s Disease
- C. David Mintz, Mount Sinai School of Medicine
- Investigating the Role of Presenilin-1 at the Synapse
- Jacqueline Payton, University of Illinois at UrbanaChampaign
- Functional Analysis of the Neurodegenerative Disease-Related Protein, Alpha-Synuclein
- Mark Rapoport, Northwestern University Medical School
- Dynamic State of Mind Does a More Plastic Cytoskeleton Prevent AB-Induced Neurogeneration in Hippocampal Neurons?
- Catherine Rehder, Virginia Commonwealth University
- The Role of Chromosome Specific Telomere Length in Age-Related Somatic Cell Aneuploidy
- Rose Reynolds, University of Illinois at UrbanaChampaign
- The Contribution of Population Heterogeneity to Mortality Plateaus
- Ritu Saini, NYU School of Medicine
- Gene Regulation by Interleukin-8 in Cultured Keratinocytes
- Scott Salsman, Oklahoma Medical Research Foundation
- Effect of Active Site Oxidation on the PTEN Tumor Suppressor
- Sara Speranza, University of New England College of Medicine
- Development of Neurosteroids as Cognitive Enhancers
- Raymond Thompson, University of South Carolina
- Effect of Aging on Inflammation During Skeletal Muscle Regeneration Following Functional Overload Induced Injury
- Maria Urso, University of Massachusetts
- Muscle Function, Disuse, and Antioxidants in Older Adults
- Laura Volpicelli, Emory University
- The Effects of Chronic Cholinergic Stimulation on Muscarinic Acetylcholine Receptor Intracellular Trafficking and Expression
- Min Zhu, University of Rochester
- Transcription Modulation by the C-Terminal Fragment of Amyloid Precursor Protein in Neurodegeneration
- Brian Zid, Caltech
- Investigating the Role of Fatty Acid Amide Hydrolase in Aging Using Drosophila Melanogaster
2001 Scholars
- Yama Akbari, University of California, Irvine
- Primary Mechanism Underlying Presenilin Mutations Calcium Dyshomesostasis or Beta-Amyloid Formation?
- David Badre, Massachusetts Institute of Technology
- Neurobiology of Cognitive Aging Human Prefrontal Cortex and Memory in Normal Aging
- Kevin Bitterman, Harvard Medical School
- A Genetic Screen for Factors that Extend Lifespan Through Caloric Restriction Pathway
- Daniela-Annenelie Bota, University of Southern California
- Regulation of Lon Protease Activity with Aging and Level of Oxidative Stress
- Todd Cannon, University of Washington
- Involvement of WRN Protein in Atherosclerogenesis
- Lynn Chien, Duke University
- Tumor Necrosis Factor Receptor Subtype-Specific Signaling in Vascular Smooth Muscle Cells
- Krishnan Dhandapani, Medical College of Georgia
- Mechanisms of Neuroprotection by Estrogen and SERMs
- Ibtissam Echchgadda, University of Texas Health Science Center, San Antonio
- Aging and DHEA-sulfotransferase in Cholesterol and Bile Acid Homeostasis
- Mark Gavin, Washington University
- Understanding the Mechanism of S Phase Arrest by the Retinoblastoma Tumor Suppressor Protein
- Kristen Homes, Washington University
- Elucidation of Components of the B3 Integrin that are Essential for Bone Resorption A Search for Anti-osteoporosis Therapeutic Targets
- Andrew Hsieh, Albert Einstein College of Medicine
- The Role of a Novel Forkhead Target Gene in Regulating Cellular Senescence
- Carianne Judge, University of Maryland
- Investigating the Role RNase-L Plays in Senescence
- Eleanor Knopp, Yale University
- The Effect of Aging on the Skeletal Response to Intermittent Treatment with PTH
- Amy Lee, Massachusetts Institute of Technology
- Age-associated Changes in the Inflammatory and Proliferative Response to Vascular Injury
- Patrick McHugh, University of Louisville
- NEUTROPHIL (PMN) SENESCENCE Can PMNs Become Too Old to Kill?
- Timothy Meyer, Washington University
- The Effect of 3-Month DHEA Supplementation in Older Adults on Vascular Reactivity
- Gail O’Kane, Massachusetts Institute of Technology
- Exploring the Relation Between Set Shifting and Memory Retrieval
- Thomas Scharshmidt, Northeastern Ohio University College of Medicine
- Analysis of Type IIA and IIB Splice Variants of Procollagen in Osteoarthritis Utilizing Laser Capture Microdissection
- Rodney Shackelford, Des Moines University of Osteopathic Medicine
- Ataxia-telangiectasia, Gene Therapy, and the Cellular Aging Process
- Alex Shpilman, Finch University of the Health Sciences/Chicago Medical School
- Impact of the SAPK-1 Pathway on the Age Related Impairment of Adipogenesis
- Faisal Siddiqui, State University of New York, Syracuse
- Numerical Densities of Myonuclei and Satellite Cells in Muscle Fiber Types in the Aging Human Lateral Cricoarytenoid Muscle An Immunohistochemical and Stereological Study Using Confocal Laser Scanning Microscopy
- Bethany Slater, Mount Sinai School of Medicine
- Alpha MSH and Aging
- Christine Spencer, University of Georgia
- The Role of Gene-Gene Interactions in Aging
- Michael Sugarman, University of California, Irvine
- Can Inclusion Body Myositis be Treated with a Beta Amyloid Vaccine?
- Junko Takeshita, Washington University
- Oxidative Damage of DNA Mechanisms for Carcinogenesis
- Doris Tham, University of California, Davis
- Actions of Peroxisome Proliferator-Activated Receptor on Diabetic Vasculopathy
- Isaiah Turnbull, Washington University
- Effect of Aging on the Heat Shock Response and Subsequent Sepsis Survival
- Christian Von Hehn, Christian-Albrechts-Universitaet, Kiel
- The Role of Kv3.1 and its Regulation in Age-related Hearing Loss
- Jill Weimer, University of Rochester
- A Transgenic Animal Model for the Disruption of Lysosome/Endosome Function A Commonality in Neurodegenerative Diseases
2000 Scholars
- Eric Agdeppa, University of California, Los Angeles
- Biological Probes for amyloid Plaques in Alzheimer’s Disease In vitro analysis of amyloid-binding Characteristics of DDNP Analogs
- Rania Al-Shami, University of Delaware
- Relative Levels of OPN-1 and OPN-2 Change During Aging
- Xinlian Chen, University of Texas Health Science Center at San Antonio
- The Response of Mice that Overexpress Catalase and Cu/Zn-SOD to Oxidative Stress
- Jay Chyung, Harvard University
- Characterizing the Effects of a Mucosal Vaccine for Alzheimer’s Disease
- Richard D’Alonzo, St. Louis University
- Physical Interaction Between Osteoblastic Transcription Factors
- Rajesh Dash, University of Cincinnati
- Phospholamban Phosphorylation as a Compensatory Mechanism of the Endangered Myocardium
- Allison Dobson, University of South Alabama
- Enhancing mtDNA Repair in Down’s and Cockayne’s Syndromes
- Delia Garigan, University of California, San Francisco
- Mapping and Characterizationof Novel Lifespan Mutations in C. Elegans
- David Gordon, University of Chicago
- Investigation of the Structure of -Amyloid Fibrils
- Elise Grenier, Northwestern University
- Regional Differences of Astrocytes in the Development or Acceleration of Alzheimer’s Disease
- Andreana Haley, University of Virginia
- A Magnetic Resonance Spectroscopic Examination of Hippocampal Volume and N-acetyl-aspartate Levels in Healthy Aging
- Jeffrey Henderson, Washington University
- Halogenation of DNA by the Myeloperoxidase System of Activated Phagocytes Implications for Carcinogenesis at Sites of Inflammation
- Rahul Kurana, Duke University
- The Role of Oxygen Free Radicals and Apoptosis in Glaucoma
- Vicki Kule, University of Michigan
- Characteristics of Disulfide Intermediate in the Aging of Phosphoglycerate Kinase
- Justine Levin, Rockefeller University
- Estrogen Effect in a Mouse Model of Alzheimer’s Disease
- Stephen Lin, Washington University
- Snflp Kinase and Aging in S. Cerevisiae
- J. Andy Mengshol, Dartmouth University Medical School
- IL-1 Regulation of Collagenase-3 in Osteoarthritis
- Renee Miller, University of Rochester
- Gene Expression Profiling in Parkinson’s Disease
- Kevin Monahan, University of Colorado
- Do Reductions in Carotid Arterial Compliance Modulate the Age-Related Decline in Arterial Baroreflex Function in Sedentary and Regularly Exercising Humans?
- Bhagavathi Ramamurthy, Pennsylvania State University
- The Effect of Glycation of Myosin on the in vitro Motility of Actin with Respect to Aging
- Jody Short, Western University of Health Sciences
- Effects of Human Apolipoprotein E Isoforms on Olfactory Nerve Plasticity in Mice
- Jennifer Stine, University of Texas Health Science Center at San Antonio
- Structural Study of FALS-Associated Cu-Zn Superoxide Dismutase Mutants
- David Sun, Medical College of Virginia/VCU
- Molecular Basis for Stroke Induced Epilepsy
- Leslie Tao, University of California, Los Angeles
- A Progesterone-Dependent Mechanism to Delay Reproductive Aging
- Robert Turner III, Oklahoma University
- Substrate Specificity of -Secretase Towards Design of Inhibitor Drugs
- Baiping Wang, University of Washington
- In Vivo Analysis of the Role of FE65 in Alzheimer’s Disease
- Fei-Shiuann Clarissa Yang, McGill University
- Role of Telomere-Associated Senescence in Wound Healing