Downloadable PDFs
- Translating advances from the basic biology of aging into clinical application
- Biology of Aging / Research Today for a Healthier Tomorrow
- Neuroprotective role of Sirt1 in mammalian models of Huntington’s disease through activation of multiple Sirt1 targets
- Sirt1 mediates neuroprotection from mutant huntingtin by activation of the TORC1 and CREB transcriptional pathway
- Finding a sirtuin truth in Huntington’s disease
- Libert Preview / Linking Caloric Intake to Behavior via Sirtuin Activity
- SRT1720 Improves Survival and Healthspan of Obese Mice
- Aging Under the Microscope
- SIRT1 Suppresses b-Amyloid Production By Activating The a-Secretase Gene ADAM10
- Two Neurons Mediate Diet-Restriction- Induced Longevity In C. Elegans
- SIRT3 Controls Cancer Metabolic Reprogramming by Regulating ROS and HIF
- SIRT3 Opposes Reprogramming of Cancer Cell Metabolism through HIF1 Destabilization
- Transcriptional Silencing And Longevity Protein Sir2 Is An Nad-Dependent Histone Deacetylase
- Calorie Restriction Extends Saccharomyces Cerevisiae Lifespan By Increasing Respiration
- Mammalian SIRT1 Represses Forkhead Transcription Factors
- Increased Wnt Signaling During Aging Alters Muscle Stem Cell Fate And Increases Fibrosis
- Stem Cell Ageing And Non-Random Chromosome Segregation
- Notch-Mediated Restoration Of Regenerative Potential To Aged Muscle
- Rejuvenation Of Aged Progenitor Cells By Exposure To A Young Systemic Environment
- Stem Cells, Ageing And The Quest For Immortality